While there are no recommendations for more frequent STI screenings for WSW (as there are for MSM), there is also no evidence to suggest that WSW should screen less frequently (per the 2014 CDC STD Treatment Guidelines, which are still under consideration). So if a doctor says you don’t need to be screened for something based on your sexual orientation — even though you have certain risk factors or symptoms — don’t be afraid to speak up or find another provider.
14. EVERYONE should get an HIV test at least once.
The CDC recommends that everyone between the ages of 13 and 64 be tested at least once in their life. We’ll talk more about the different kinds of HIV tests in a little bit. For more information, check out the CDC guide to HIV testing.
15. But that doesn’t necessarily mean you ONLY need one HIV test in your whole lifetime.
If you change partners or have unprotected sex, you should probably be tested annually, suggests Leone. You should also be tested more frequently if you’re in a high-risk group, which could include any of the following: You’ve had sex with someone who might be HIV-positive, you’ve had sex with someone and you don’t know their HIV status, you have multiple partners, you’ve had sex with someone who might have multiple partners, you’re a man who has sex with men, you have a history of drug injection, you’re a commercial sex worker, you live in a community where HIV is particularly prevalent, etc.
There are no hard and fast recommendations for how often most of these groups should be tested for HIV, so it’s important to talk about your risk with a doctor and determine the best screening guidelines for you. For the most part, you should be tested (or at least ask your doctor about your risk) annually unless you’re in a mutually monogamous relationship and you’ve both been tested.
16. If you’re a man who has sex with men, you should get an HIV test every year. If you have multiple partners or anonymous partners, you should be screened more often (at 3-6 month intervals).
17. Pregnant women should be tested for syphilis, HIV, chlamydia, and hepatitis B (and retested if necessary). They should also be screened for gonorrhea and hepatitis C if they are at risk.
You’re “at risk” for gonorrhea if you are under 25, if you’re over 25 but have new or multiple partners, if you live in a community where gonorrhea is common, if you’ve had gonorrhea before, if you’ve had other STIs, if you don’t use condoms consistently, if you’re a commercial sex worker, or if you use drugs. You’re “at risk” for hepatitis C if you have a history of drug-injection use or a history of blood transfusion or organ transplant before 1992.
Here’s what you need to know about testing for STIs if you’re a transgender man or woman, or if your partner is a transgender man or woman.
Transgender individuals have a gender that is different from what they were assigned at birth. Because gender identity is different than sexual orientation, it’s important to note that trans men and trans women may have sex with any gender. It’s also important to remember that some trans people have had gender confirmation surgery while others have not. All of these factors can influence which STI tests you should be getting and how frequently you should be getting them.
18. Unfortunately, the CDC does not have concrete screening guidelines for trans people.
However, it’s possible to assess your risk by considering your genital anatomy, your partner’s genital anatomy, your sexual behaviors, and other outside risk factors. “It should come down to organs and risk,” Dr. Madeline Deutsch, clinical director at the Center of Excellence for Transgender Health. “Providers should be talking about who you are having sex with, what’s going where, and what are the circumstances that surround that sexual behavior.”
For instance, a trans man with a vagina should get regular Pap tests and STI screenings consistent with the guidelines for cisgender women who have sex with men or women. “A vagina should be screened regardless of who it’s attached to,” says Deutsch. And if you’re having receptive anal sex or have multiple partners with a penis, follow MSM guidelines, regardless of your own gender or sexual identity, or your partners’.
After gender confirmation surgery, the recommendations may be even more personalized. If you have had vaginoplasty, for instance, you may be at a reduced risk for certain infections since there’s no vaginal mucosa and it doesn’t open to the abdominal cavity, explains Deutsch. However, if you have had phalloplasty, it’s not yet known if you would be at an increased or decreased risk of any particular infections, so talk to a doctor about your personal risk factors.
19. Because STI screening for trans people will be based on your unique sexual behaviors and anatomy, it’s important to assess your risk with a healthcare provider to determine which tests you need.
It can be incredibly difficult and intimidating to disclose your gender identity, sexual orientation, and specific sexual behaviors to a doctor, which is why it’s crucial to find a provider who is well versed in this. You can search for LGBT-friendly providers at GLMA.org, WPATH.org, or trans-health.com. These are databases where providers have specifically submitted their offices as being LGBT-friendly or specializing in LGBT care. (Editor’s note: Have other resources you trust? Please post them in comments.)
20. You’ll typically only be tested for herpes if you have symptoms or if you suspect you’ve been exposed. But feel free to ask for the test if you think you’re at risk.
Approximately 1 in 6 adults in the U.S. have genital herpes, and most people don’t know they have it, according to the CDC. Still, routine screening for herpes isn’t recommended (based on cost-effectiveness and the likelihood for false positives in low-risk populations). If you have any symptoms (lesions on or around the mouth, genitals, or rectum that break and leave painful ulcers, which may take weeks to heal), if you’ve been with someone who was diagnosed with herpes, or if you’ve had unsafe sex or sex with multiple partners, ask your doctor if you can be tested.
21. Before you even think about HPV testing, consider getting the HPV vaccine.
HPV (or human papillomavirus) is the most common STI out there, and almost all sexually active people get it at some point in their lives, according to the CDC. Most HPV infections clear on their own, but a few high-risk strains can lead to genital warts or even cancer. The surest defense against HPV is getting vaccinated at an early age. The CDC Advisory Committee on Immunization Practices recommends routine vaccination of all females and males at ages 11 or 12 (but they can get them as early as age 9). They also recommend that women catch up on the vaccine by age 26 and men catch up by age 21 if they haven’t already gotten all three shots. However, men can also be vaccinated up to age 26.
Even if you’ve missed the boat, some experts still suggest getting the vaccine as an adult if you’re at risk. So talk to a doctor about it if you think you would benefit. Just remember that insurance won’t cover the cost after a certain age.
22. If you have a vagina, you should get an HPV test at age 30. But you may get one earlier if you have an abnormal Pap test.
Starting at age 21, all women should be getting a Pap test every 3 years, which looks for cervical cell changes that could point to cancer, per the American College of Obstetricians and Gynecologists. If you’re a trans man with a vagina, you should be following these guidelines, too. If you’re a trans woman and you’ve had bottom surgery, talk to your doctor for specific screening guidelines based on your anatomy.
If your doctor notices anything abnormal in your Pap test, they may call for additional testing — like an HPV test or colposcopy (where they closely examine your uterus and often collect a sample for testing). Otherwise, you wouldn’t have an HPV test until the age of 30, when it’s recommended that you get a Pap test and HPV test together. From ages 30-65, it’s recommended that you get these two tests together every 5 years OR just a Pap test alone every 3 years. However, if you ever have any abnormal Pap test or HPV test, you’ll need to be screened more frequently (at least for a period of time).
23. There is currently no HPV test for anyone with a penis, but there are a few precautions you can take.
Obviously, get vaccinated if you haven’t already. But what should you do if you think you’ve been exposed? Your doctor can do a visual exam for genital warts caused by HPV, since most people actually miss these on their own, says Leone. He also suggests a digital rectal exam and sometimes a rectal pap for men over 30 who may be at risk for HPV. These can check for infections, lesions, or masses in the anal canal, and they would be especially beneficial for those who have receptive anal intercourse.
24. And if you’re ever experiencing ANY strange symptoms, head to your doctor or a health clinic immediately to get tested.
If you notice any itching, burning, unusual discharge, redness, rash, lesions/sores, uncomfortable urination, unusual odor, pain in the penis/testicles/vagina/vulva/pelvic region/lower abdomen, or anything else that seems really off, get it checked out. There are some STIs that you might only get tested for if you have certain symptoms (like trichomoniasis, bacterial vaginosis, and sometimes syphilis), so don’t assume that you’ll just deal with it at your next annual check-up.
25. Chlamydia and gonorrhea are typically urine tests or swab tests.
The doctor might take a cell sample from the cervix, penis, vagina, or anus or test any discharge (per Planned Parenthood). If you’ve had oral sex or anal sex, they may also collect swabs from your throat or rectum.
26. Syphilis testing is typically done with a blood test.
The doctor might also test the fluid from a sore (per Planned Parenthood).

27. Testing for trichomoniasis and bacterial vaginosis are both done by testing discharge from the vagina or the urethra (in the case of trichomoniasis).
28. HPV testing is a swab test that examines cell samples from the cervix.
29. Genital warts are diagnosed through a physical exam or colposcopy.
30. There are a few different ways to test for herpes.
If you currently have symptoms or lesions, your doctor can take a swab of the area, which is called a direct test. If a swab test is negative, your doctor may take a blood test to confirm. Most providers recommend type-specific serologic tests, whichare blood tests that can detect the antibodies for either herpes simplex virus type 1 (HSV-1) or type 2 (HSV-2).
31. There are few different ways to test for HIV.
The most common HIV test is the antibody screening test (also called immunoassay), which detects the antibodies your body makes against HIV (per the CDC). This can be either a blood test or an oral swab. Either of those can be run as either a lab test or a rapid test, which gives results in 30 minutes or less. But keep in mind: Lab-based blood tests typically pick up the virus before the oral tests and the rapid tests do. If the test is negative and you may have been exposed in the past 3 months, you should get another test after 3 months, since it’s possible that your immune system hasn’t made the antibodies yet or that the test wasn’t able to pick them up yet.
A newer type of HIV test looks for both antibodies and the antigen (which is part of the virus itself). This one is a blood test and it may be able to detect the virus as soon as 3 weeks after exposure.
There are also at-home HIV tests, like the Home Access HIV-1 Test System (which tests a finger-prick sample that you send to a lab) and the OraQuick In-Home HIV Test (which is an oral swab that gives rapid results).
Regardless of which test you use, any positive result would need to be confirmed by a follow-up lab test. There are several different kinds of these as well, and you can find out more about them here.
32. Talking about STI testing with your partner is normal and necessary.
Even though it seems like it, this is not an exhaustive list of everything there is to know about STIs and testing. There are so many unique cases and exceptions to the rules, which is why this should be an ongoing conversation — not a pamphlet to glance at every once in a while. Talk with your partner about what you’re doing now, what you’ve done in the past, and what you’ve been tested for recently. Then have this conversation with your doctor to make sure you’re getting the right tests at the right frequency.